1-AD by Hi-Tech Pharmaceuticals is based upon a naturally occurring metabolite for many animals including man that has properties far different from standard testosterone in the body.
In January 2005 the supplement industry witnessed the banning of the best natural legal hormonal products ever produced. We are referring to the 1-Test & 1-AD family of supplements. These "delta-ones" (as they were referred to) changed the entire legal hormone market. There was nothing like them before their introduction and there has been nothing like them since. "Delta-ones" included the original 1-AD's (1-androstenedione and 1-androstenediol) and the 1-test esters and ethers. Hi-Tech's 1-AD converts to 1-Testosterone is more of a mild hormone that will give you cleaner gains and dramatic strength increases.
1-Androsterone aka 1-androstene-3b-ol-17-one is still available on the U.S. market and is the key component of 1-AD. In a recent study released in the Journal of Applied Physiology, the oral prohormone 1-androstene-3b-ol-17-one was found to be as potent milligram-for-milligram to Testosterone enathate, the gold standard for Testosterone products!
Very few dietary supplements have been subjected to a clinical study. However, the active prohormone 1-androstene-3b-ol-17-one was the subject of a clinical study at the West Texas A&M University, the California Baptist University and the University of Texas at Austin. The results showed 1-androstene-3b-ol-17-one to be significantly more powerful than it would appear structurally. The 9 males gained an average lean mass of 10.4 lbs and an increase in strength of 92.2 lbs in total load on bench/squat/deadlift. These are significant gains from a prohormone. The researchers concluded that the prohormone supplement contributed to robust improvements in muscle mass and strength in resistance trained.
Lean Muscle Gains
Low to No Estrogen Conversion
Minimal Water Retention
Quicker Lean Muscle Growth
Hi-Tech Pharmaceuticals is an Innovator in the Bodybuilding and Prohormone industry being one of the first companies to introduce many of the prohormones that have entered the marketplace over the last decade. Researchers at Hi-Tech recently developed a proprietary process called CyclosomeTechnology. This one-of-a-kind technology brought to you by the leaders in Prohormones involves the entrapment of hydrophobic prohormones and other Testosterone boosting compounds in the form of water-soluble Prohormone–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to combine the relative advantages of CDs and liposomes into one system, namely Prohormone-in-CD-in-liposome systems called Cyclosome's.
You can think of all this in terms of a ‘Trojan Horse,’ passing through the liver unharmed and intact. As opposed to being destroyed in the liver like all other hormonal products on the market, past and present. This new Cyclosome technology allows the ‘Trojan Horse’ to deliver prohormones and testosterone boosters to the systemic circulation by the intestinal lymphatic route, circumventing first-pass inactivation in the liver for the very first time. Almost all previous Oral capsules and tablets manufactured to increase testosterone — including Testosterone itself — are involved in the "first pass affect" which renders the active compounds virtually useless.
Cyclosome Technology — the most advanced liposomal delivery technology ever developed for bioavailability is the answer to getting poorly absorbed Testosterone boosting compounds and legal prohormones into the body so they can work ! The pharmaceutical industry has embraced this cutting-edge technology in recent years and now 1-Testosterone will be one of the first to utilize it in a testosterone booster and anabolic agent.
For Cyclosome preparation, an overall understanding of the interaction between CDs and lipid components of liposomes is necessary for this complex. Hi-Tech has developed a Double-loading technique, which is a revolutionary strategy to prohormone release and increase prohormone-loading capacity. The Cyclosome approach can be useful in increasing prohormone solubility and vesicles stability, in controlling the in vivo fate of hydrophobic compounds and in avoiding burst release of prohormones from the vesicles.
To obtain a stable Cyclosome, the CDs should have a higher affinity to prohormone molecules compared with liposomal membrane lipids. Cyclosomes prepared by Hi-Tech's double-loading technique are the most advanced targeted prohormone delivery system ever developed because they have a fast onset action with prolonged prohormone release process and the significantly enhanced prohormone-loading capacity.